ManuCyte

ManuCyte focuses on the development of an intelligent, modular manufacturing platform for flexible, patient-specific cell production which will increase efficiency of personalised cell production in terms of quality, throughput, and costs. This objective will be reached by combining several high-sophisticated technologies such as

• a modular and scalable concept for the setup of cell production platforms, which is based on plug-ins and allows a flexible composition of functionalities, extension of capacities, as well as fast ramp up.
• a micro-fluidic component which provides cell culture medium specifically customised for each cell culture.
• bioreactors with integrated sensor technology, which are capable for highly automated processes as well as the associated incubation component
• the application of a cost-neutral cleanroom and sterilisation concept to keep cell cultures free of contaminations from the environment and between different cell cultures.
• optical and biochemical inline monitoring methodologies, which enable the evaluation of cell status within the production process
• a MES (Manufacturing Execution System) with LIMS (Laboratory Information and Management System) functionalities
• a self-learning knowledge-based cell behaviour model and advanced cell process control functionalities.